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Epigallocatechin gallate

Epigallocatechin gallate

MW: 458.37
Formula: C22H18O11

What is Epigallocatechin gallate?

Epigallocatechin gallate belongs to the family of catechins. It contains 3 phenol rings and has very strong antixoidant properties.

Distribution

Epigallocatechin gallate is the main active component if green tea leaves. Black tea leaves also contain epigallocatechin gallate but in much lower quantities. That's because black tea leaves are fermented, during which many of the cathechins are oxidized to darker coloured molecules (theaflavin and thearubigen).

Health Benefits of Epigallocatechin gallate

Epigallocatechin gallate possess the most potent antioxidant activity of the catechins. Epigallocatechin gallate may provide health effects by protecting our cells from oxidative damage from free radicals. A number of chronic disease have been associated with free radical damage, including cancer, arteriosclerosis, heart diseases and accelerated aging. Epigallocatechin gallate interferes with many enzyme systems: it inhibits fast-binding and reversible fatty acid synthase, increases tyrosine phosphorylation of the insulin receptor, activation of ornithine decarboxylase.
Epigallocatechin gallate can protect the DNA in the human cells from ultraviolet and visible radiation-induced damage.
Epigallocatechin gallate may be effective in promoting fat oxidation and lowering body weight.

Research Reviews

Green Tea Polyphenol Epigallocatechin Gallate Affects Gene Expression of Breast Cancer Cells Transformed by the Carcinogen 7,12-Dimethylben(a)Anthracene
Epigallocatechin gallate supplementation alleviates diabetes in rodents.

Abstracts

Benefits of Epigallocatechin-Gallate

Synonyms

EGCG



 
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