Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with diet-induced hypercholesterolemia.
Journal of Agriculture and Food Chemistry. 2004 May 19;52(10):2879-86
This study investigated the studied the cholesterol lowering properties of polymethoxylated flavones, mainly tangeretin, and citrus flavanone glucosides (hesperidin and naringin) in hamsters. The researchers found that rats fed with a diet containing 1% polymethoxylated flavones showed a significantly reduced (up to 40%). Similar results were obtained with a mixture of hesperidin and naringin, but they had to use 3 times higher levels of these phytochemicals, implying a lower hypolipidemic potency of this mixture. The study concluded that polymethoxylated flavones have cholesterol- and triacylglycerol-lowering potential.
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