Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production. American Journal of Clininal Nutrition, 2005 December, 82(6):1260-8 Estrogen protects women against cardiovascular disease by reducing the levels of inflammatory markers. The objective of this study was to investigate if isolated soy isoflavones also have this cardioprotective property. One hundred seventeen postmenopausal women participated in this dietary trial. One group consumed isoflavone-enriched cereal for 8 weeks. The group who consumed isoflavones showed ower C-reactive protein concentrations but no other significant on other plasma inflammatory markers were observed. C-reactive protein is a protein that increases during systemic inflammation and is an indication for cardiovascular disease risk.
Soy Protein Containing Isoflavones Reduces the Size of Atherosclerotic Plaques without Affecting Coronary Artery Reactivity in Adult Male Monkeys. Journal of Nutrition, 2005 December, 135(12):2852-6 This study determined the long-term effect of soy protein concentrate intake on the development of atherosclerosis and vascular reactivity in adult male monkeys. The researchers found that soy protein intake reduced atherosclerosis by 34 percent, but did not influence endothelium-dependent or -independent arterial function.
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