Effect of dietary level of phytic acid on hepatic and serum lipid status in rats fed a high-sucrose diet.
Biosci Biotechnol Biochem. 2004 Jun;68(6):1379-81
This study investigated the effects of the intake of different levels of phytic acid on hepatic and serum lipid status by rats fed with a diet high in sugar. The levels of sodium phytate ranged from 0.02% to 10%. The researchers found that phytic acid reduced the hepatic levels of triglyceride and cholesterol. The activity of lipogenic enzymes was also reduced. However, very high dietary levels of phytic acid (10%) resulted in a drastically depressed growth and food intake.
The effect of phytic acid on in vitro rate of starch digestibility and blood glucose response.
American Journal of Clinical Nutrition. 1983 December;38(6):835-42
This study investigated the effect of the dietary intake of phytic acid on the glycemic index. The researchers found that the phytic acid level was negatively correlated with the glycemic index. Phytic acid reduced the digestion of raw starch up to 50%. The addition of calcium reduced this effect.
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